Protein Details: Glutamate receptor 2.7

Protein ID

ICDB_Pro_1273

Protein Name

Glutamate receptor 2.7

Gene Name

GLR2.7; At2g29120; T9I4.20

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

952 amino acids

AlphaFoldDB

AF-Q8LGN0-F1-model_v4.pdb

Function

Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.

Sequence

MKVMNPRKTNNTFMYYFVLFVCGFVLMEGCLGQNQTTEIKVGVVLDLHTSFSKLCLTSINISLSDFYKYHSDYTTRLAIHIRDSMEDVVQASSAALDLIKNEQVSAIIGPRTSMQAEFMIRLADKSQVPTITFSATCPLLTSINSPYFVRATLDDSSQVKAIAAIVKSFGWRNVVAIYVDNEFGEGILPLLTDALQDVQAFVVNRCLIPQEANDDQILKELYKLMTMQTRVFVVHMPPTLGFRFFQKAREIGMMEEGYVWLLTDGVMNLLKSNERGSSLENMQGVLGVRSHIPKSKKLKNFRLRWEKMFPKKGNDEEMNIFALRAYDSITALAMAVEKTNIKSLRYDHPIASGNNKTNLGTLGVSRYGPSLLKALSNVRFNGLAGEFELINGQLESSVFDVINIIGSEERIIGLWRPSNGIVNAKSKNTTSVLGERLGPVIWPGKSKDVPKGWQIPTNGKMLRVGIPVKKGFLEFVDAKIDPISNAMTPTGYCIEIFEAVLKKLPYSVIPKYIAFLSPDENYDEMVYQVYTGAYDAVVGDVTIVANRSLYVDFTLPYTESGVSMMVPLKDNKNTWVFLRPWSLDLWVTTACFFVFIGFIVWILEHRVNTDFRGPPHHQIGTSFWFAFSTMNFAHREKVVSNLARFVVLVWCFVVLVLIQSYTANLTSFFTVKLLQPTVTNWKDLIKFNKNIGYQRGTFVRELLKSQGFDESQLKPFGSAVECDELFSNGTITASFDEVAYIKVILSQNSSKYTMVEPSFKTAGFGFVFPKKSPLTDDVSRAILNVTQGEEMQHIENKWFKKPNNCPDLNTSLSSNHLSLSSFWGLFLIAGIASFLALLIFVANFLYEHKHTLFDDSENSFRGKLKFLVRNFDEKDIKSHMFKENAVHNVSSPITQGSSSPLTDQSTPLPRSPEQYRELELRRVSSISSGELFTTQSEQVEDEESAIIQCEGE

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed predominantly in leaves

DOI ID

10.1126/science.292.5521.1486b; 10.1038/45471; 10.1111/tpj.13415; 10.1093/oxfordjournals.molbev.a004165; 10.1126/science.1088305

RefSeq

NP_180476.3